VETACORTYL

METHYLPREDNISOLONE INJECTION.

LONG-ACTING, ANTI-INFLAMMATORY CORTICOSTEROID.

PRODUCT

VETACORTYL is an aqueous suspension of 40mg/ml methyleprednisolone acetate for injection. 5ml multidose vial.

ACTION

Methylprednisolone is a potent anti-inflammatory synthetic corticosteroid with prolonged systemic and local effects. It has marked gluconeogenic effects. The tendency to promote sodium/water retention Is very weak.

INDICATIONS

VETACORTYL is indicated for the management of chronic inflammatory conditions, including arthritis, chronic dermatitis, and other inflammatory or allergic conditions, where a long-acting effect is required.

SPECIFIC INDICATIONS

CATS: For the management of chronic stomatitis (trench-mouth), the eosinphilic granuloma complex, (rodent ulcer, eosinophilic plaque, granulomatous stomatitis, linear granuloma), allergic dermatitis and miliary eczema.

DOGS: Arthritis, chronic allergic dermatitis, bronchial asthma.

HORSES: Arthritis, bursitis, tendonitis, and other musculo-skeletal inflammatory disorders.

DOSAGE

Where VETACORTYL is used for maintenance therapy, the initial dosage should be gradually reduced until the lowest effective dose is established.

GENERAL RECOMMENDATIONS

CATS: 10-20mg s/c or i/m (2-4mg/kg) repeated as necessary. (The antipruritic effects usually last 2-6 weeks depending on the underlying condition).

DOGS: 1mg/kg (average dose 20mg) s/c or i/m. Repeat with caution weekly, or as necessary.

Intra-articular. Approximately 20mg, depending on the size of the joint.

HORSES: 200mg i/m, repeated as necessary with decreasing dosages until maintenance is achieved.

Intra-articular/Intrasynovial: 40-240mg depending on the joint space.

INTRALESIONAL THERAPY

VETACORTYL may be mixed 1:2 with local anaesthetic and injected intradermally, 0.1ml per site at a number of sites, depending on the lesion.

PRECAUTIONS

Prolonged corticosteroid therapy, excessive dosage, or too frequent administration, may suppress the hypothalamic-adrenal axis and induce a Cushingoid syndrome. For this reason, methylprednisolone acetate injection should be used with caution, especially in the dog.

Cats are considered more resistant to glucocorticoid side-effects than dogs. Methylprednisolone may be more active and clinically effective in cats than dogs.

CONTR-INDICATIONS

Do not use when active infection exists without suitable antibiotic cover, or in cases of diabetes mellitus, Cushingoid syndrome, osteoporosis, gastric ulceration, pregnancy, etc.

COMMENT

In the treatment of certain chronic inflammatory and pruritic conditions in cats, eg. Miliary eczema, methylprednisolone acetate may be more appropriate than progestogens.

With long term treatment, progestogens may be diabetogenic and may induce other potential adverse effects in cats.

Licensed under the Animal Remedies Act 1967, No. 4823.

Prescription Animal Remedy (P.A.R) Class 1, for use only following a Veterinary Consultation.

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